Engaging in fragile settings is challenging, but there is much to learn from the work Development Assistance Committee (DAC) members are doing to support fragile contexts on the ground. Drawing on case study research and a secondary literature review assembled as part of the Fit for Fragility project, this chapter offers guidance for navigating these substantively, strategically and institutionally complex environments. Though organisational fitness challenges are most visible at country level, they often reflect the quality of engagement by all parts of the organisation, from the local to the global level. Beyond individual organisations, the challenge also resides in strengthening coherence by ensuring effective co-ordination and – where relevant – collaborating across the Humanitarian Development Peace Nexus. Being fit for fragility, in this sense, is strongly contingent on being fit for collaboration.