The goods needed to vaccinate, protect and test during the COVID-19 pandemic are produced across many different countries. This brief tells the tale of three products ‒ vaccines, face masks and tests ‒ and highlights the role of trade in the fight against COVID-19. International markets and global supply chains played a pivotal role during the COVID-19 pandemic: first, by helping countries avail themselves of the goods needed to address the pandemic; second, by providing a means to ease temporary supply constraints; and third, by enabling access to key components to ramp up production to meet surging demand.