This report provides an overview of green infrastructure planning and the use of nature-based solutions in Italy. It identifies key challenges and trade-offs and provides recommendations to promote their uptake across the different levels of government. The report also analyses four case studies that have been identified in agreement with the Italian Ministry of Infrastructure and Transport: the Green Node in Bari, the metro line M4 in Milan, the Ridracoli Dam in Emilia-Romagna, and the railway line Bicocca-Catenanuova.