This paper provides a common framework for financial institutions – and particularly development finance institutions – on how to carry out due diligence to identify, respond to, and publicly communicate on environmental and social risks associated with projects and assets they finance. Financial institutions are increasingly being called to enable provisions of financing towards projects, infrastructure and other assets that will help achieve societal and development objectives, including the Sustainable Development Goals and the Paris Agreement. Embedding responsible business conduct (RBC) into their activities and across their value chains can help them meaningfully contribute to these objectives. This paper is designed for financial institutions that wish to implement the recommendations of the OECD Guidelines for Multinational Enterprises with respect to RBC due diligence in the context of project and asset finance transactions. It will provide practical recommendations to financial institutions on key aspects of the RBC due diligence process, including on stakeholder engagement, managing client’s confidentiality, providing for or contributing to the remediation process, etc.