The OECD Test Guidelines Programme established in 2022 a group of experts on methodologies to test and evaluate chemicals for their thyroid disruption properties. Thyroid function is a complex process where multiple biological mechanisms are at stake and represent as many targets of chemical perturbation. Between 2014 and 2024, member countries and dedicated research centres have devoted resources to developing and standardising in vitro assays for thyroid disruption. This document includes consensus reports from OECD on the assessment of the validation status of individual thyroid in vitro assays from the EU-NETVAL activity in the period 2017-2022; assays are listed in chronological order of their progression in the assessment process.
Thyroid in vitro methods: assessment reports by the thyroid disruption methods expert group
Reports assessing the validation status of assays from the EU-NETVAL activities
OECD Series on Testing and Assessment
